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The Tangled Trio of Gut Microflora, Junk Food, and Mental Health

Have you ever experienced a feeling of sadness after eating a cheesious pizza at Burgerking?

Well,Most people”ll respond “NO” with a bursting laughter after hearing this question which indicates that the idea is utterly absurd and comical to them.Eating pizza or any kind of junk food usually and unfortunately makes us all feel happy. But that happiness actually costs the happiness of good bacteria residing your gut.

Our gut is teeming with a lot of microorganisms ; bacteria, yeast etc what makes the botanical garden or “Microbiome” of gut. Besides playing important roles in nutrition, drug metabolism and immunomodulation , the microflora has a significant impact on our mental health.

It can be understood by the fact that 95% of serotonin in our body is synthesized by our gut microbiome and not by our brain. Most of these bacteria contain enzyme “Tryphtophan hydroxylase” that converts tryptophan into 5-hydroxytryphtophan which is later converted to serotonin.

Serotonin also known as “feel good hormone” makes us feel happier, focused, emotionally stable and calmer. Serotonin also contributes to the formation of melatonin;a hormone that regulates sleep-wake cycle.

The sad part about consuming junk food is that most of their constituents are lethal to gut bacteria i.e the additives and preservatives. Moreover, the processed fats oxidize and generate free radicals that can damage bacterial membranes leading to their death. Eventually a person comes up with a condition in which he/she has reduced levels of serotonin and other neurotransmitters. The fact can be related to sudden burst of laziness and lethargy after consuming a whole lot of junk food. Studies also claim that prolonged consumption of processed food can have long term effect on your mental health leading to neuropsyciatric disorders like ADHD, schizophrenia and anxiety disorders. This phenomenon helps explain why individuals from affluent backgrounds are more prone to developing these disorders, in contrast to individuals with modest means who cannot afford to indulge in extravagant lifestyle choices, such as frequent partying and luxurious diets that can contribute to the development of these conditions.

Research suggests that therapies focused on enhancing and restoring the gut microbiome, such as Fecal Microbiota Transplantation (FMT), may be a valuable treatment approach for psychiatric disorders. Transplantation of fecal bacteria from healthy donors has been found to positively impact mental health by reducing symptoms of psychiatric disorders, including depression, anxiety, bipolar disorder, and schizophrenia, by reintroducing diverse and beneficial microbial communities into the gut, promoting a healthier gut-brain axis and suggesting a promising adjunctive treatment strategy for mental health management.

The idea was confirmed by Mar;Gracias and colleagues through a variety of experiments on NOD( non-obese diabetic) and B6 strain of lab mice.

The question is “If junk foods are making you feel sad, what kind of foods can make you feel happier?”

The simple answer is “The food that makes your gut bacteria happy, actually makes “you” feel happy”.

One good option is Probiotics;The live microorganisms. They are abundantly found in fermented foods like yogurt, kefir, sauerkraut etc. Researchers have used the term “psycobiotics” for them in regard to their positive impact on mental health. They help flourish the gut microbiome leading to instant rush of serotonin that’d last longer and help you unlock your full potential.

So, next time you feel like your “inner lion” is sleeping, it’s time to reassess your dietary choices and look after the “Lilliputian organisms” residing inside you.

Rutba Emaan
Bachelors in Pathology Lab Sciences, Sargodha Medical College, UOS

About the author: Meet Rutba Eman, a dedicated and aspiring medical professional currently pursuing her Bachelor’s degree in Pathology Lab Sciences at Sargodha Medical College, University of Sargodha. Rutba is driven by a passion to unravel the intricacies of human biology and disease mechanisms. Through her writing, she hopes to inspire others to explore the wonders of life sciences and foster a deeper understanding of the medical field. With her unique blend of scientific expertise and writing enthusiasm, Rutba is poised to make a meaningful impact in the world of science communication.

4 Comments

  • Mir M Adil

    Really amazing work. The best part is, its presentation. The way it is written is interesting and unique. Keep it up.

  • Hamza Ali

    Very Informative article Keep it up.
    .

  • Yusra

    Glad to read about the junk food and related mental health problems.. well written and informative… keep it up

  • Shabana nazeer

    Rutba Eman’s article, “The Tangled Trio of Gut Microflora, Junk Food, and Mental Health,” delves into the complex interplay between diet, gut health, and psychological well-being. The article effectively highlights how junk food consumption can disrupt gut microbiota, leading to potential mental health issues such as anxiety and depression. Eman skillfully weaves together scientific research and accessible language, making the topic engaging for a broad audience. However, while the article is informative, it could benefit from a more in-depth exploration of potential solutions or practical advice for readers. Overall, it’s a thought-provoking read that underscores the importance of diet in maintaining mental health.

  • Rutba Emaan

    Gratitude🙏🏻
    For providing a prestigious platform to showcase my skills

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